Although several high-throughput methods are routinely used for process development there are still many challenges to address. Examples include potential analytical bottlenecks, effects of scale and formats on data, interpretation of data, and adequate control of experimental conditions at the microscale. Analytical bottlenecks here relate to the limited number of quick methods for the determination of critical quality attributes, especially for biomolecules that are not monoclonal antibodies, and/or to challenges associated with assessing drug product stability. Both the scale of HTPD experiments and the formats used can affect results.
The scope of the meetings cover process development from upstream processing, through downstream processing, to stable formulation.
UNESCO World Heritage sites
The meetings will if possible continue to be held in cities cited on the UNESCO World Heritage list.
The 2012 conference was held in Centre des Congrès du Palais des Papes, a World Heritage site, in Avignon, France.